Computational Modeling of Aortic Heart Valves

Computational modeling is an excellent tool with which to investigate the mechanics of the aortic heart valve. The setting of the heart valve presents complex dynamics and mechanical behavior in which solid structures interact with a fluid domain. There currently exists no standard approach, a variety of strategies have been used to address the different aspects of modeling the heart valve. Differences in technique have included the imposition of the load, the portion of the cardiac cycle simulated, the inclusion of the fluid component of the problem, the complexity of anatomical parameters, and the definition of material characteristics. Simplifications reduce computational costs, but could compromise accuracy. As advancements in modeling techniques are made and utilized, more physiologically relevant models are possible. Computational studies of the aortic valve have contributed to an improved understanding of the mechanics of the normal valve, insights on the progression of diseased valves, and predictions of the durability and efficacy of surgical repairs and valve replacements.